I don't take anything. Jet lag gets me every time, and I make regular trips across the Atlantic. Pretty much I try to stay up when I fly west, and generally adjust my clock quickly. Going east is much harder, I try to get a bit of sleep on the airplane, usually unsuccessfully, and just try to stay up until evening in Europe.
One easy solution is to fly biz class

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I can't quite imagine what you Aussies have to go through, pretty much every flight is very long-haul, and going from AUS to Europe is brutal. I've done India and Middle East - US West Coast and that nearly did me in.